Tuesday, April 19, 2011

F. Prostate cancer

Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive system. Prostate cancer usually grows slowly and can often be cured or managed successfully, however in the aggressive case, The cancer cells can spread from the prostate to other parts of the body, particularly the bones and lymph nodes
1. Symptoms
a. Painful or burning sensation in urination
b. Inability to urinate or difficulty in starting urine stream
c. Inability to empty bladder
d. Blood in urine
e. Continual pain in the lower back, pelvis or upper thighs
f. Frequent, urgent need to urinate
g. Erectile dysfunction
h. Problems during sexual intercourse
i. Etc

2. Risk factros
a. Age.
Risk of prostate cancer increases with age. it may be due to wear and tear or inability of the immune function in fighting against oxidation of the prostate cells.
b. Heredity
Genetic alternation genes may contribute to prostate cancer risk, as suggested by associations with race, family, and specific gene variants. Prostate cancer occurs about 60% more often in African American men than in white American.
c. Diet
Diet high in saturated and trans fat may be a contributing factor of prostate cancer, as the disease is much more common in countries where meat and dairy products are dietary staples.
d. Viral
In 2006, researchers found a Xenotropic MuLV-related virus or XMRV, with human prostate tumors.
e. Sexual transmitting diseases
Infection caused by infection with the sexually transmitted infections chlamydia, gonorrhea, or syphilis seems to increase risk of prostate cancer.
f. Etc.

2. Free radical and prostate cancer
Prostate cancer involves a malignant tumor growth within the prostate gland. Recent study showed that chronic inflammation of the prostate gland and high free radical load contribute to DNA damage and genomic instability, leading to cancerous or benign tumors, due to oxidative stress provoked by toxins, dietary fat consumption, or high level of androgens, etc.. Cancerous tumours can grow through your prostate and spread to other parts of your body through the bloodstream or the lymph system, where they may grow and form secondary tumours.

3. Antioxidants and prostate cancer
a. Lycopene
In a randomized study, 15 of 26 men scheduled for radical prostatectomy for organ confined malignancy were given lycopene supplements, 15 mg twice a day for over the 3 weeks were found to have smaller volume tumors and surgical margins were less likely to be positive.
b. The manganese superoxide dismutase (MnSOD)
The manganese superoxide dismutase MnSOD is the cells primary defense against free radical mediated damage by encoding an antioxidant enzyme (SOD2).
c. Vitamin C
Dr. J. Leuchaeur, who successfully works with prostate cancer patients, recommends as much as 60 grams (60,000mgs) per day for prostate cancer along with a Primitive Diet. This has been used as the entire prostate treatment as vitamin C helped to prevent the free radical damage that is associated with cancer.
d. Vitamin E
Vitamin E beside stops the production of ROS formed when fat undergoes oxidation, it also decrease incidence of prostate cancer.
e. Carotene
By strengthening growth regulatory signsls between cells and preventing damage prostate cells from reproducing and forming tumors.
f. Selenium and vitamin E
The Selenium and Vitamin E Cancer Prevention Trial (SELECT) is taking place in the United States, Puerto Rico, and Canada. SELECT is trying to find out if taking selenium and/or vitamin E supplements can prevent prostate cancer in men age 50 or older. by protecting cells from damage caused by unstable molecules.
g. Etc.